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Forskolin, Tocris Bioscience™
Adenylyl cyclase activator
Marca: Tocris Bioscience 1099/10
183.20 EUR hasta el 2025-07-30
Use el código promocional "24078" para aplicar la oferta.
| Cantidad | 10 mg |
|---|
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Descripción
Forskolin, or coleonol, is a cell-permeable, potent, reversible and rapid activator of adenylyl cyclase, an enzyme that converts ATP to cAMP and pyrophosphate (EC50 = 0.5 μM). In combination with 5 other compounds, forskolin enables chemical reprogramming of mouse embryonic fibroblasts to pluripotent stem cells, without genetic factors: Valproic acid, sodium salt (Cat. No. 2815), RepSox (Cat. No. 3742), Tranylcypromine hydrochloride (Cat. No. 3852), CHIR 99021 (Cat. No. 4423) and 3-Deazaneplanocin A hydrochloride (Cat. No. 4703). In combination with IBMX (Cat. No. 2845), forskolin induces neural differentiation of mesenchymal stem cells by downregulating neuron restrictive silencer factor. In a rat model of Huntington's disease-like neurodegeneration, forskolin also exhibits neuroprotective effects. Hypotensive and vasodilatory agent.Water-soluble analog, NKH 477 (Cat. No. 1603), and Forskolin synthesized to Ancillary Material Grade also available.
For more information about how Forskolin may be used, see our protocol: Transdifferentiating Fibroblasts into Neurons.
Identificadores de productos químicos
| 66575-29-9 | |
| 410.507 | |
| forskolin, colforsin, coleonol, colforsina, colforsine, colforsinum, boforsin, colforsine french, colforsinum latin, colforsina spanish | |
| CHEBI:42471 | |
| CC(=O)OC1C(C2C(CCC(C2(C3(C1(OC(CC3=O)(C)C=C)C)O)C)O)(C)C)O |
| C22H34O7 | |
| OHCQJHSOBUTRHG-KGGHGJDLSA-N | |
| 47936 | |
| [(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-etenil-6,10,10b-trihidroxi-3,4a,7,7,10a-pentametil-1-oxo-5,6,6a,8,9,10-hexahidro-2H-benzo[f]cromen-5-il] acetato |
Especificaciones
| (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(Acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho[2,1-b]pyran-1-one | |
| C22H34O7 | |
| forskolin, colforsin, coleonol, colforsina, colforsine, colforsinum, boforsin, colforsine french, colforsinum latin, colforsina spanish | |
| CC(=O)OC1C(C2C(CCC(C2(C3(C1(OC(CC3=O)(C)C=C)C)O)C)O)(C)C)O | |
| 410.507 | |
| CHEBI:42471 | |
| >98% |
| 66575-29-9 | |
| 10 mg | |
| OHCQJHSOBUTRHG-KGGHGJDLSA-N | |
| [(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-etenil-6,10,10b-trihidroxi-3,4a,7,7,10a-pentametil-1-oxo-5,6,6a,8,9,10-hexahidro-2H-benzo[f]cromen-5-il] acetato | |
| 47936 | |
| 410.51 |
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