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Higromicina B, Thermo Scientific Chemicals

Hygromycin B, CAS # 31282-04-9, is an aminoglycoside compound showing antibiotic activity that kills bacteria through the inhibition of protein synthesis. It also presents anthelmintic activity. | CAS: 31282-04-9 | C20H37N3O13 | 527.524 g/mol

61.20€ - 172.00€

Identificadores de productos químicos

CAS 31282-04-9
Fórmula molecular C20H37N3O13
Peso molecular (g/mol) 527.524
Número MDL MFCD06795479
Clave InChI GRRNUXAQVGOGFE-BBMONYMYSA-N
PubChem CID 134129613
Nombre IUPAC (3'S,3aS,4S,4'S,5'R,6R,6'R,7R,7aS)-4-[(1R,2S,3R,5S,6S)-3-amino-2,6-dihidroxi-5-(metilamino)ciclohexil]oxi-6'-[(1S)-1-amino-2-hidroxietil]-6-(hidroximetil)espiro[4,6,7,7a-tetrahidro-3aH-[1,3]dioxolo[4,5-c]piran-2,2'-oxano]-3',4',5',7-tetrol
SMILES CNC1CC(C(C(C1O)OC2C3C(C(C(O2)CO)O)OC4(O3)C(C(C(C(O4)C(CO)N)O)O)O)O)N
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Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
15403419
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Thermo Scientific Alfa Aesar
J60681.MC
100 mg
61.20€
100 miligramos
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15413419
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Thermo Scientific Alfa Aesar
J60681.MD
250 mg
83.30€
250 miligramos
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15493409
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Thermo Scientific Alfa Aesar
J60681.03
1 g
172.00€
1 g
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Descripción

Descripción

An aminoglycoside antibiotic that kills bacteria by inhibiting protein synthesisHygromycin B is used for the selection and maintenance of prokaryotic and eukaryotic cells that contains the hygromycin resistance gene. This gene is frequently used as a selectable marker in research on plants. It stabilizes the transfer ribonucleic acid (tRNA)-ribosomal acceptor site, thereby inhibiting translocation. In addition to this, it serves as an aminoglycosidic antibiotic which inhibits protein synthesis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Hygromycin is an aminoglycosidic compound that shows antibiotic activity. It is produced by Streptomyces hygroscopicus
  • Hygromycin acts against both prokaryotic and eukaryotic cells, having the ability to inhibit protein synthesis. It also stabilizes the transfer ribonucleic acid (tRNA)-ribosomal acceptor site, thereby inhibiting translocation. This compound prevents ribosome translocation during translation elongation by binding the 30S rRNA proximal to the ribosomal E, P, and A sites

Application

  • In clinical and plant research, this compound can be used as a marker to select and maintain prokaryotic and eukaryotic cells containing the hygromycin resistance gene
  • Hygromycin also presents an anthelmintic activity against nematode parasites of chickens
Especificaciones

Identificadores de productos químicos

31282-04-9
527.524
GRRNUXAQVGOGFE-BBMONYMYSA-N
(3'S,3aS,4S,4'S,5'R,6R,6'R,7R,7aS)-4-[(1R,2S,3R,5S,6S)-3-amino-2,6-dihidroxi-5-(metilamino)ciclohexil]oxi-6'-[(1S)-1-amino-2-hidroxietil]-6-(hidroximetil)espiro[4,6,7,7a-tetrahidro-3aH-[1,3]dioxolo[4,5-c]piran-2,2'-oxano]-3',4',5',7-tetrol
C20H37N3O13
MFCD06795479
134129613
CNC1CC(C(C(C1O)OC2C3C(C(C(O2)CO)O)OC4(O3)C(C(C(C(O4)C(CO)N)O)O)O)O)N

Especificaciones

Hygromycin B
Lyophilized Powder
Marrón
MFCD06795479
14,4852
GRRNUXAQVGOGFE-BBMONYMYSA-N
(3'S,3aS,4S,4'S,5'R,6R,6'R,7R,7aS)-4-[(1R,2S,3R,5S,6S)-3-amino-2,6-dihidroxi-5-(metilamino)ciclohexil]oxi-6'-[(1S)-1-amino-2-hidroxietil]-6-(hidroximetil)espiro[4,6,7,7a-tetrahidro-3aH-[1,3]dioxolo[4,5-c]piran-2,2'-oxano]-3',4',5',7-tetrol
134129613
Hygromycin B
31282-04-9
C20H37N3O13
UN3462
Miscible with water,methanol,buffer solution and ethanol; Immiscible with less polar solvents.
CNC1CC(C(C(C1O)OC2C3C(C(C(O2)CO)O)OC4(O3)C(C(C(C(O4)C(CO)N)O)O)O)O)N
527.524
527.53
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Seguridad y manipulación

Seguridad y manipulación

GHS H Statement
H300-H310-H330-H334-H318-H317
Fatal if swallowed.
Fatal in contact with skin.
Fatal if inhaled.
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Causes serious eye damage.
May cause an allergic skin reaction.

P260-P262-P264b-P270-P271-P272-P280-P284-P285-P301+P310-P302+P350-P304+P340-P305+P351+P338-P310-P330-P333+P313-P361-P363-P501c

H300+H310+H330-H317-H318-H334

missing translation for 'dotInformation' : Transport Hazard Class: 6.1; Packing Group: I; Proper Shipping Name: TOXINS, EXTRACTED FROM LIVING SOURCES, SOLID, N.O.S.

missing translation for 'einecsNumber' : 250-545-5

missing translation for 'rtecsNumber' : WK2130000

missing translation for 'tsca' : No

Recommended Storage : Keep cold

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Documentos

Documentos

Product Certifications

RUO – Research Use Only

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