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RYR2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
145.00€ - 410.00€
Especificaciones
Antigene | RYR2 |
---|---|
Concentrazione | 0.33 mg/mL |
Applicazioni | Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry, Western Blot |
Classificazione | Polyclonal |
Coniugato | Unconjugated |
Código de producto | Marca | Quantità | Precio | Cantidad y disponibilidad | |||||
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Código de producto | Marca | Quantità | Precio | Cantidad y disponibilidad | |||||
16899244
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Proteintech
19765-1-AP-20UL |
20 μL |
145.00€
20 microlitros |
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16889244
|
Proteintech
19765-1-AP-150UL |
150 μL |
410.00€
150 microlitros |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | |||||
Descripción
This antibody detects a band at ∽250 kDa which has been reported.
Dihydropyridine receptor (DHPR) is a surface membrane protein critical for the excitation-contraction coupling of striated muscle. DHPR and the sarcoplasmic reticulum ryanodine receptor (RyR) are two key components of the intracellular junctions, where depolarization of the surface membrane is converted into the release of Ca2+ from internal stores. The alpha1-subunit of the DHPR contains a cytoplasmic loop which is thought to be involved in the interactions with RyR. Phosphorylation of the DHPR alpha1-subunit is also thought to play a role in the functional interaction of DHPR and RyR. Mutation in DHPR alpha1 results in excitation-contraction uncoupling, leading to muscular dysgenesis, a complete inactivity in developing skeletal muscles. Cells that do not express RyR also lack excitation-contraction coupling and exhibit a severalfold reduction in Ca2+ current density.Especificaciones
RYR2 | |
Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry, Western Blot | |
Unconjugated | |
Rabbit | |
Mouse, Human | |
E9Q401, Q92736 | |
20191, 6262 | |
Peptide | |
Primary | |
-20°C | |
RYR2 |
0.33 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
ARVC2, ARVD2, ryanodine receptor 2 (cardiac), ryanodine receptor 2, cardiac, RYR2, VTSIP | |
RYR2 | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |
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