missing translation for 'onlineSavingsMsg'
Learn More

ACTN4 Mouse anti-Human, Mouse, Rat, Clone: 1E12B8, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 66628-1-IG-150UL

 View more versions of this product

Product Code. 16818685

  • 410.00€ / 150µL

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Description

This antibody recognizes 105 kDa of endogenous ACTN4 protein in various lysates.

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis.
Specifications

Specifications

ACTN4
Monoclonal
1 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
O43707, P57780, Q9QXQ0
Actn4
ACTN4 Fusion Protein Ag13549
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG1
Immunohistochemistry (Paraffin), Western Blot
1E12B8
Unconjugated
ACTN4
ACTININ 4, actinin, alpha 4, ACTN4, Alpha actinin 4, F actin cross linking protein, FSGS, FSGS1, Non muscle alpha actinin 4
Mouse
Protein G
RUO
60595, 63836, 81
-20°C
Liquid
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Certificates
Promotions

Promotions

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.