missing translation for 'onlineSavingsMsg'
Learn More

ACTN4 Mouse anti-Human, Mouse, Rat, Clone: 1E12B8, Proteintech

Mouse Monoclonal Antibody

1081.84 DKK - 3058.99 DKK

Specifications

Antigen ACTN4
Clone 1E12B8
Concentration 1 mg/mL
Applications Western Blot, Immunohistochemistry (Paraffin)
Classification Monoclonal
View More Specs

Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16828685
View Documents
Proteintech
66628-1-IG-20UL
20 μL
1081.84 DKK
20µL
Please to purchase this item. Need a web account? Register with us today!
16818685
View Documents
Proteintech
66628-1-IG-150UL
150 μL
3058.99 DKK
150µL
Please to purchase this item. Need a web account? Register with us today!
Description

Description

This antibody recognizes 105 kDa of endogenous ACTN4 protein in various lysates.

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis.
Specifications

Specifications

ACTN4
1 mg/mL
Monoclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
ACTININ 4, actinin, alpha 4, ACTN4, Alpha actinin 4, F actin cross linking protein, FSGS, FSGS1, Non muscle alpha actinin 4
Actn4
IgG1
Protein G
Antibody
1E12B8
Western Blot, Immunohistochemistry (Paraffin)
Unconjugated
Mouse
Rat, Mouse, Human
O43707, P57780, Q9QXQ0
60595, 63836, 81
ACTN4 Fusion Protein Ag13549
Primary
-20°C
ACTN4
Videos
SDS
Documents

Documents

Product Certifications
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.